cannabinoid
CBD
Also known as: CannabidiolCannabidiol (CBD) is a non-intoxicating cannabinoid found in cannabis and hemp — unlike THC, it doesn't produce a high. It's sold as oils, capsules, edibles, and topicals, and in full-spectrum, broad-spectrum, and isolate forms.
Educational reference only — not medical advice. These statements have not been evaluated by the FDA, and this information is not intended to diagnose, treat, cure, or prevent any disease. Talk to a healthcare provider before use.
Typical dose
No standard dose. Research spans 15 mg to several hundred mg daily; many sources suggest starting around 10–20 mg and adjusting.
Onset
Sublingual 15–30 min · oral 30–90 min · inhaled within minutes
Duration
Sublingual 4–6 h · oral 6–8 h · inhaled 2–4 h
Legal status
Hemp-derived CBD (from plants ≤0.3% Delta-9 THC by dry weight) is federally legal under the 2018 Farm Bill; state laws vary. Marijuana-derived CBD remains federally controlled.
Common forms
Oil / tinctureCapsuleEdibleTopicalVape
Safety
Generally well tolerated. Reported effects include drowsiness, reduced appetite, diarrhea, and fatigue; high doses have been linked to elevated liver enzymes in trials. Product quality varies widely in an unregulated market — look for a third-party Certificate of Analysis.
Interactions
Processed by the CYP3A4 and CYP2C19 liver enzymes, so it can interact with medications that use the same pathways. Talk to a healthcare provider if you take prescription medication.
Who should avoid
People who are pregnant or nursing, and anyone taking interacting medications, should consult a healthcare provider before use.
Products with this
No listed products reference this yet.
Sources
- Millar SA, et al. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans. Front Pharmacol. 2018.
- Bonn-Miller MO, et al. Labeling Accuracy of Cannabidiol Extracts Sold Online. JAMA. 2017.
- Agriculture Improvement Act of 2018 (Farm Bill), Pub. L. No. 115-334.