cannabinoid
Delta-9 THC
Also known as: Delta-9-tetrahydrocannabinol, THCDelta-9 THC is the main psychoactive cannabinoid in cannabis — the compound most responsible for the intoxicating effects. It works mainly by binding CB1 receptors in the brain and nervous system.
Educational reference only — not medical advice. These statements have not been evaluated by the FDA, and this information is not intended to diagnose, treat, cure, or prevent any disease. Talk to a healthcare provider before use.
Typical dose
Start low, go slow. A low edible dose is commonly cited as 2.5–5 mg; response varies widely by tolerance, body chemistry, and whether it's taken with food.
Onset
Inhaled within minutes · edibles 30 min–2 h
Duration
Inhaled 1–3 h · edibles 4–8 h
Legal status
Hemp-derived Delta-9 THC within the 0.3%-by-dry-weight limit is federally legal under the 2018 Farm Bill, but many states restrict it; local laws vary.
Common forms
EdibleBeverageVape / flowerTincture
Safety
Higher doses raise the chance of anxiety, paranoia, rapid heart rate, and impaired coordination. Edibles hit later and last longer than inhalation, which makes over-consumption easy. Don't drive or operate machinery after use.
Interactions
Can amplify the effects of alcohol and other sedatives. Discuss with a healthcare provider if you take prescription medication.
Who should avoid
People who are pregnant or nursing, under 21, or with a personal or family history of psychosis should avoid THC.
Products with this
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Sources
- National Institute on Drug Abuse. Cannabis (Marijuana) DrugFacts, 2024.
- Huestis MA. Human cannabinoid pharmacokinetics. Chem Biodivers. 2007.
- Agriculture Improvement Act of 2018 (Farm Bill), Pub. L. No. 115-334.